Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.66 |
| ▸ | DRD3 | P35462 | 4/20 | 0.66 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTR2C | P28335 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848845 | 1.00 | DRD2 (0.66) | DRD2DRD3SLC6A2SLC6A4ADRA1D | |
| SCHEMBL30855329 | 0.88 | DRD2 (0.66) | DRD2DRD3SLC6A2SLC6A4ADRA1D | |
| SCHEMBL3848840 | 0.85 | DRD2 (0.61) | DRD2DRD3HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL4076895 | 0.84 | DRD2 (0.53) | DRD2DRD3SLC6A2SLC6A4ADRA1D | |
| Hydrochloric Acid SCHEMBL4076893 | 0.84 | DRD2 (0.53) | DRD2DRD3SLC6A2SLC6A4ADRA1D | |
| SCHEMBL4082053 | 0.83 | DRD2 (0.57) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| SCHEMBL4502971 | 0.83 | DRD2 (0.65) | DRD2DRD3ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL3329691 | 0.81 | DRD2 (0.63) | DRD2DRD3SLC6A4ADRA1DADRA1A | |
| Hydrochloric Acid SCHEMBL3329696 | 0.81 | DRD2 (0.63) | DRD2DRD3SLC6A4ADRA1DADRA1A | |
| SCHEMBL3847619 | 0.81 | DRD2 (0.65) | DRD2DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594294-A1 | DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS | The United States of America, as represented by the Secretary, Department of Health and Human Services (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024072930-A1 | DOPAMINE D3/D2 RECEPTOR PARTIAL AGONISTS FOR THE TREATMENT OF NEUROPSYCHIATRIC DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-04-04 | — | — | WO | disclosed |