Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.57 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.50 |
| ▸ | HTR3B | O95264 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.50 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082050 | 0.87 | ADRA1D (0.52) | DRD2ADRA1DADRA1AADRA1BDRD4 | |
| Hydrochloric Acid SCHEMBL3329696 | 0.84 | DRD2 (0.63) | DRD2ADRA1DADRA1AADRA1BDRD4 | |
| Hydrochloric Acid SCHEMBL3329691 | 0.84 | DRD2 (0.63) | DRD2ADRA1DADRA1AADRA1BDRD4 | |
| SCHEMBL30855296 | 0.83 | DRD2 (0.66) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL3848845 | 0.83 | DRD2 (0.66) | DRD2ADRA1DADRA1AADRA1BDRD3 | |
| SCHEMBL3847616 | 0.83 | DRD2 (0.61) | DRD2ADRA1BDRD4DRD3ALDH1A1 | |
| SCHEMBL3849464 | 0.82 | FFAR4 (0.51) | DRD2ADRA1DADRA1AADRA1BDRD4 | |
| SCHEMBL7410473 | 0.80 | ALDH1A1 (0.68) | DRD2ADRA1DADRA1AADRA1BDRD4 | |
| SCHEMBL3853464 | 0.80 | DRD2 (0.60) | DRD2DRD4DRD3ALDH1A1 | |
| SCHEMBL7549051 | 0.79 | DRD2 (0.65) | DRD2ADRA1DADRA1AADRA1BDRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7473692-B2 | Sulfonamide derivatives as D3-receptor ligands | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2009-01-06 | — | — | US | claimed |