Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666412 | 0.82 | HPGD (0.52) | CA1CA2KMT2AMEN1HPGD | |
| SCHEMBL30855345 | 0.76 | ALDH1A1 (0.58) | CA1CA2CA4KMT2AMEN1 | |
| SCHEMBL9726573 | 0.72 | KMT2A (0.57) | CA1CA2KMT2AMEN1HPGD | |
| SCHEMBL11526534 | 0.72 | CES2 (0.48) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL28274214 | 0.72 | KMT2A (0.67) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL11609313 | 0.72 | TPMT (0.54) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL16976467 | 0.71 | KDM4E (0.39) | CA1CA2RAPGEF4KMT2AMEN1 | |
| SCHEMBL17831135 | 0.71 | KDM4E (0.48) | KMT2AMEN1SMN1; SMN2POLBIGFBP3 | |
| SCHEMBL14075229 | 0.71 | KDM4E (0.39) | CA1CA2RAPGEF4KMT2AMEN1 | |
| SCHEMBL9973592 | 0.70 | CA1 (0.48) | CA1CA2CA4LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886685-A | 1, 3-diaryl formyl benzene compound and preparation method and application thereof | 浙江工业大学 | 2024-04-16 | — | — | CN | disclosed |