SCHEMBL30855477

SCHEMBL30855477

O=Cc1cc(-c2cccc(-c3nnn[nH]3)c2)ccc1O

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24101966 1.00 ERN1 (0.51) ERN1
SCHEMBL673067 0.78 ESR1 (0.57)
SCHEMBL12761250 0.77 GP6 (0.37)
SCHEMBL5318854 0.75 TRIM24 (0.41)
SCHEMBL29953141 0.75 TRIM24 (0.41)
SCHEMBL4655029 0.74 GP6 (0.49)
SCHEMBL30554383 0.74 ERN1 (0.69) ERN1
SCHEMBL30554384 0.74 ERN1 (0.69) ERN1
SCHEMBL29751505 0.74 ERN1 (0.69) ERN1
SCHEMBL26606756 0.74 ERN1 (0.69) ERN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113801087-B Benzo-six-membered ring derivatives as DPP-4 inhibitors and uses thereof 山东百极地长制药有限公司 2024-08-30 CN disclosed
CN-113801088-B Benzo six-membered ring derivative and application thereof 山东百极地长制药有限公司 2024-04-26 CN disclosed