Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ABL1 | P00519 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | BCR | P11274 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674152 | 0.87 | HSD17B1 (0.57) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL4655029 | 0.86 | GP6 (0.49) | ESR1MEN1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL672712 | 0.86 | ESR1 (0.46) | ESR1MEN1KMT2AABL1ABCB1 | |
| SCHEMBL12761250 | 0.86 | GP6 (0.37) | ESR1MEN1KMT2AHSD17B1HSD17B2 | |
| SCHEMBL859970 | 0.84 | HSD17B1 (0.52) | ESR1HSD17B1HSD17B2ESR2CYP3A4 | |
| SCHEMBL595369 | 0.84 | PKM (0.44) | ESR1MEN1KMT2AESR2MMP3 | |
| SCHEMBL6893920 | 0.83 | NR1H2 (0.38) | ESR1MEN1KMT2A | |
| SCHEMBL28400263 | 0.82 | PKM (0.43) | ESR1MEN1KMT2AESR2MMP3 | |
| SCHEMBL16158539 | 0.80 | TP53 (0.41) | CYP3A4CYP2C9FGFR1 | |
| SCHEMBL9941579 | 0.79 | ESR1 (0.56) | ESR1ABL1ABCB1BCRHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-29 | — | — | US | disclosed |
| WO-2012024495-A1 | USE OF AZIDES IN SYNTHESIS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-02-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130225819-A1 | USE OF AZIDES IN SYNTHESIS | ABL1, ABL2, TST | ESR1 2449/4885MEN1 3042/4885KMT2A 1704/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.