Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.36 |
| ▸ | HTR2C | P28335 | 5/20 | 0.36 |
| ▸ | HTR2B | P41595 | 4/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 6/20 | 0.34 |
| ▸ | BRD4 | O60885 | 5/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2144622 | 1.00 | HTR2A (0.36) | HTR2AHTR2CHTR2BDGAT1HTR1A | |
| SCHEMBL759941 | 0.89 | DGAT1 (0.35) | HTR2AHTR2CDGAT1KMONPC1 | |
| SCHEMBL16437423 | 0.84 | KMO (0.50) | HTR2AHTR2CHTR2BDGAT1HTR1A | |
| SCHEMBL30385717 | 0.84 | KMO (0.48) | HTR2AHTR2CHTR2BDGAT1HTR1A | |
| SCHEMBL30485520 | 0.84 | HTR2A (0.39) | HTR2AHTR2CHTR2BDGAT1HTR1A | |
| SCHEMBL2144138 | 0.84 | HTR2A (0.39) | HTR2AHTR2CHTR2BDGAT1HTR1A | |
| SCHEMBL2318217 | 0.84 | KMO (0.48) | HTR2AHTR2CHTR2BDGAT1HTR1A | |
| SCHEMBL30032612 | 0.81 | DGAT1 (0.37) | HTR2AHTR2CHTR2BDGAT1HTR1A | |
| SCHEMBL29365472 | 0.80 | RECQL (0.47) | ADRA2AKMONPC1 | |
| SCHEMBL27718799 | 0.80 | RECQL (0.47) | ADRA2AKMONPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121509-B | JAK inhibitor compounds and uses thereof | 河南迈英诺医药科技有限公司 | 2024-04-26 | — | — | CN | disclosed |