Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.50 |
| ▸ | CCR8 | P51685 | 1/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 10/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30241144 | 0.77 | CCR1 (0.47) | CCR1CCR8METAP2CYP2A6DGAT1 | |
| SCHEMBL27627478 | 0.76 | CCR1 (0.46) | CCR1CCR8METAP2CYP2A6DGAT1 | |
| SCHEMBL3745071 | 0.74 | CCR1 (0.62) | CCR1CCR8METAP2NOS3NOS2 | |
| SCHEMBL1456972 | 0.74 | CCR1 (0.62) | CCR1CCR8METAP2NOS3NOS2 | |
| SCHEMBL20390886 | 0.72 | CYP2A6 (0.44) | CCR1CCR8MASP2NOS3NOS2 | |
| SCHEMBL16715991 | 0.72 | CCR1 (0.67) | CCR1CCR8METAP2NOS3NOS2 | |
| SCHEMBL14576669 | 0.71 | TGFBR1 (0.47) | CCR1CCR8METAP2CYP2A6DGAT1 | |
| SCHEMBL4036263 | 0.71 | CCR1 (0.58) | CCR1CCR8METAP2NOS3NOS2 | |
| SCHEMBL196966 | 0.70 | CCR1 (1.00) | CCR1CCR8METAP2NOS3NOS2 | |
| SCHEMBL29388304 | 0.70 | CCR1 (1.00) | CCR1CCR8METAP2NOS3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881669-A | Condensed ring heteroaryl compounds and uses thereof | 比西切姆有限公司 | 2024-04-12 | — | — | CN | disclosed |