Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 13/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.33 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855633 | 0.76 | CCR1 (0.50) | CCR1CCR8CYP2A6METAP2DGAT1 | |
| SCHEMBL24542668 | 0.74 | DGAT1 (0.36) | CCR1CCR8CYP2A6METAP2DGAT1 | |
| SCHEMBL30241144 | 0.73 | CCR1 (0.47) | CCR1CCR8CYP2A6METAP2DGAT1 | |
| SCHEMBL14576669 | 0.71 | TGFBR1 (0.47) | CCR1CCR8CYP2A6METAP2DGAT1 | |
| SCHEMBL27628728 | 0.70 | SMPD3 (0.42) | CYP2A6 | |
| SCHEMBL3745071 | 0.70 | CCR1 (0.62) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL1456972 | 0.70 | CCR1 (0.62) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL27992258 | 0.69 | SCN2A (0.55) | — | |
| SCHEMBL16715991 | 0.69 | CCR1 (0.67) | CCR1CCR8CYP2A6METAP2TGFBR1 | |
| SCHEMBL5020175 | 0.68 | CCR1 (0.54) | CCR1CCR8CYP2A6METAP2TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1681805-A | Novel imidazole compounds as transforming growth factor (TGF) inhibitors | PFIZER PROD INC (US) | 2005-10-12 | — | — | CN | disclosed |