Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 9/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 8/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25435072 | 0.96 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19TSHRCYP2D6 | |
| SCHEMBL30558734 | 0.96 | CYP1A2 (0.41) | CYP1A2CYP3A4CYP2C19TSHRCYP2D6 | |
| SCHEMBL30856034 | 0.89 | ALDH1A1 (0.37) | TSHRALDH1A1HSD17B10TDP1MAPK1 | |
| SCHEMBL30856159 | 0.87 | NPBWR1 (0.38) | ALDH1A1HSD17B10LMNAMAPTSMN1; SMN2 | |
| SCHEMBL30558733 | 0.86 | TACR1 (0.38) | TSHRALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL25434998 | 0.86 | TACR1 (0.38) | TSHRALDH1A1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL30855768 | 0.83 | MAPT (0.41) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL30855702 | 0.82 | MAPT (0.40) | CYP1A2CYP3A4TSHRALDH1A1HSD17B10 | |
| SCHEMBL30305525 | 0.80 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19TSHRCYP2D6 | |
| SCHEMBL26312738 | 0.80 | CYP1A2 (0.40) | CYP1A2CYP3A4CYP2C19TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4561562-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026128-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |