⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30856403 | 0.83 | CYP1A2 (0.41) | — | |
| SCHEMBL30855874 | 0.82 | KDM4E (0.30) | — | |
| SCHEMBL30855748 | 0.73 | LMNA (0.32) | — | |
| SCHEMBL10076076 | 0.72 | TDP1 (0.36) | — | |
| SCHEMBL30856300 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL14908669 | 0.64 | CNR2 (0.44) | — | |
| SCHEMBL18164170 | 0.64 | KMT2A (0.40) | — | |
| SCHEMBL28483269 | 0.62 | CNR2 (0.42) | — | |
| SCHEMBL30695536 | 0.62 | CNR2 (0.42) | — | |
| SCHEMBL31468224 | 0.62 | ERN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4561562-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026128-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |