Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30855874 | 0.84 | KDM4E (0.30) | MAPTKDM4ELMNAHTTNPSR1 | |
| SCHEMBL30856006 | 0.83 | — | — | |
| SCHEMBL30855748 | 0.74 | LMNA (0.32) | LMNAHTTALDH1A1 | |
| SCHEMBL10076076 | 0.74 | TDP1 (0.36) | MAPTHTTALDH1A1KMT2A | |
| SCHEMBL30856300 | 0.74 | MEN1 (0.33) | MAPTLMNAHTTALDH1A1KMT2A | |
| SCHEMBL30856168 | 0.66 | CYP1A2 (0.47) | CYP1A2MAPTKDM4ELMNACCR6 | |
| SCHEMBL31716448 | 0.66 | HTR2A (0.39) | MAPTKDM4ELMNAHTTNPSR1 | |
| SCHEMBL14908669 | 0.65 | CNR2 (0.44) | CYP1A2MAPTLMNANPSR1KMT2A | |
| SCHEMBL18164170 | 0.65 | KMT2A (0.40) | CYP1A2LMNAHTTALDH1A1KMT2A | |
| SCHEMBL21960948 | 0.65 | KMT2A (0.38) | CYP1A2MAPTLMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120152713-A | Tricyclic aryl derivatives and compositions and methods thereof | 昂胜医疗科技公司 | 2025-06-13 | — | — | CN | disclosed |
| EP-4561562-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026128-A2 | TRICYCLIC ARYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |