Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 18/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30856579 | 0.85 | KIF18A (0.49) | KIF18A | |
| SCHEMBL31500367 | 0.83 | KIF18A (0.47) | KIF18A | |
| SCHEMBL30856628 | 0.83 | KIF18A (0.63) | KIF18A | |
| SCHEMBL31500397 | 0.82 | KIF18A (0.45) | KIF18A | |
| SCHEMBL31018526 | 0.77 | KIF18A (0.42) | KIF18A | |
| SCHEMBL31018610 | 0.77 | KIF18A (0.47) | KIF18A | |
| SCHEMBL31500403 | 0.77 | KIF18A (0.47) | KIF18A | |
| SCHEMBL31018522 | 0.77 | KIF18A (0.42) | KIF18A | |
| SCHEMBL31018654 | 0.76 | KIF18A (0.43) | KIF18A | |
| SCHEMBL31018694 | 0.76 | KIF18A (0.43) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917405-A | KIF18A protein inhibitors | 杭州邦顺制药有限公司 | 2024-04-23 | — | — | CN | disclosed |