Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.34 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.34 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.34 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15990725 | 0.77 | KDM4E (0.56) | ALDH1A1KDM4EAKR1C3TSHRSMN1; SMN2 | |
| SCHEMBL13737314 | 0.77 | KDM4E (0.56) | ALDH1A1KDM4EAKR1C3TSHRSMN1; SMN2 | |
| SCHEMBL13736733 | 0.77 | KDM4E (0.56) | ALDH1A1KDM4EAKR1C3TSHRSMN1; SMN2 | |
| SCHEMBL30064356 | 0.76 | HPGDS (0.46) | ALDH1A1KDM4EKCNH2RAB9A | |
| SCHEMBL29085191 | 0.76 | HPGDS (0.46) | ALDH1A1KDM4EKCNH2RAB9A | |
| SCHEMBL29085213 | 0.76 | HPGDS (0.46) | ALDH1A1KDM4EKCNH2RAB9A | |
| SCHEMBL29085210 | 0.76 | HPGDS (0.46) | ALDH1A1KDM4EKCNH2RAB9A | |
| SCHEMBL4890246 | 0.73 | KDM4E (0.47) | ALDH1A1KDM4EAKR1C3TSHRSMN1; SMN2 | |
| SCHEMBL390175 | 0.73 | KDM4E (0.47) | ALDH1A1KDM4E | |
| SCHEMBL13826035 | 0.72 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117813302-A | Substituted tetrahydrofuran-2-carboxamides as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2024-04-02 | — | — | CN | disclosed |