Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 13/20 | 0.58 |
| ▸ | VEGFA | P15692 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556093 | 1.00 | EPAS1 (0.58) | EPAS1VEGFA | |
| SCHEMBL18688473 | 0.78 | EPAS1 (0.71) | EPAS1VEGFA | |
| SCHEMBL18688474 | 0.78 | EPAS1 (0.71) | EPAS1VEGFA | |
| SCHEMBL13518494 | 0.77 | HTR1A (0.46) | EPAS1 | |
| SCHEMBL9933801 | 0.77 | HTR1A (0.46) | EPAS1 | |
| SCHEMBL21005070 | 0.75 | EPAS1 (0.67) | EPAS1VEGFA | |
| SCHEMBL31497804 | 0.74 | VEGFA (0.50) | EPAS1VEGFA | |
| SCHEMBL31497893 | 0.74 | EPAS1 (0.44) | EPAS1VEGFA | |
| SCHEMBL17671198 | 0.74 | EPAS1 (1.00) | EPAS1VEGFA | |
| SCHEMBL21741352 | 0.74 | EPAS1 (0.68) | EPAS1VEGFA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49948-E1 | Aryl ethers and uses thereof | PELOTON THERAPEUTICS, INC. (US) | 2024-04-30 | — | — | US | disclosed |