Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 12/20 | 0.50 |
| ▸ | BCL2 | P10415 | 15/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.35 |
| ▸ | BAD | Q92934 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30857713 | 1.00 | BCL2L1 (0.50) | BCL2L1BCL2HTR1AADRA1DADRA1A | |
| SCHEMBL30857621 | 0.93 | BCL2L1 (0.41) | BCL2L1BCL2HTR1AADRA1DADRA1A | |
| SCHEMBL30857750 | 0.92 | BCL2L1 (0.58) | BCL2L1BCL2HTR1AADRA1DADRA1A | |
| SCHEMBL30857660 | 0.92 | BCL2L1 (0.58) | BCL2L1BCL2HTR1AADRA1DADRA1A | |
| SCHEMBL30857681 | 0.91 | BCL2L1 (0.51) | BCL2L1BCL2HTR1AADRA1DADRA1A | |
| SCHEMBL30857684 | 0.85 | BCL2L1 (0.50) | BCL2L1BCL2HTR1AADRA1DADRA1A | |
| SCHEMBL30857631 | 0.84 | BCL2L1 (0.48) | BCL2L1BCL2HTR1AADRA1DADRA1A | |
| SCHEMBL30857664 | 0.81 | BCL2L1 (0.50) | BCL2L1BCL2 | |
| SCHEMBL30857596 | 0.80 | BCL2L1 (0.44) | BCL2L1BCL2BCL2L11CYP2C9MCL1 | |
| SCHEMBL21751667 | 0.79 | BCL2L1 (0.59) | BCL2L1BCL2BCL2L11CYP2C9MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |