Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 13/20 | 0.59 |
| ▸ | BCL2 | P10415 | 16/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BAD | Q92934 | 2/20 | 0.38 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751607 | 0.93 | BCL2L1 (0.51) | BCL2L1BCL2ALDH1A1MAPTTSHR | |
| SCHEMBL23164961 | 0.93 | BCL2L1 (0.51) | BCL2L1BCL2ALDH1A1MAPTTSHR | |
| SCHEMBL21751641 | 0.92 | BCL2L1 (0.49) | BCL2L1BCL2ALDH1A1MAPTTSHR | |
| SCHEMBL21751544 | 0.86 | SLC6A3 (0.44) | BCL2L1BCL2ALDH1A1MAPTTSHR | |
| SCHEMBL23165399 | 0.86 | SLC6A3 (0.44) | BCL2L1BCL2ALDH1A1MAPTTSHR | |
| SCHEMBL21751591 | 0.84 | BCL2L1 (0.62) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL28447129 | 0.84 | BCL2L1 (0.62) | BCL2L1BCL2BCL2L2 | |
| SCHEMBL30857677 | 0.81 | BCL2L1 (0.51) | BCL2L1BCL2BADBCL2L11CYP2C9 | |
| SCHEMBL30857629 | 0.81 | BCL2L1 (0.51) | BCL2L1BCL2BADBCL2L11CYP2C9 | |
| SCHEMBL29317976 | 0.80 | BCL2L1 (0.59) | BCL2L1BCL2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020041406-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2020-02-27 | — | — | WO | disclosed |