Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | SMYD2 | Q9NRG4 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29246127 | 0.80 | SMYD2 (0.41) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL16433235 | 0.80 | LTA4H (0.48) | LTA4HSIGMAR1CYP3A4CXCR4TACR1 | |
| SCHEMBL16432291 | 0.80 | LTA4H (0.48) | LTA4HSIGMAR1CYP3A4CXCR4TACR1 | |
| SCHEMBL24803467 | 0.80 | LTA4H (0.57) | LTA4HSIGMAR1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL13308369 | 0.80 | LTA4H (0.57) | LTA4HSIGMAR1CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL6731676 | 0.79 | LMNA (0.50) | SIGMAR1ALDH1A1 | |
| SCHEMBL16439837 | 0.77 | LTA4H (0.52) | LTA4HSIGMAR1CYP3A4CXCR4CYP2C19 | |
| SCHEMBL5077219 | 0.77 | LTA4H (0.58) | LTA4HSIGMAR1CYP3A4CXCR4TACR1 | |
| SCHEMBL19617349 | 0.77 | MAPK1 (0.40) | SMYD2CYP3A4HTTSMN1; SMN2 | |
| SCHEMBL30927563 | 0.77 | MAPK1 (0.40) | SMYD2CYP3A4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |