Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 11/20 | 0.57 |
| ▸ | BCL2 | P10415 | 13/20 | 0.46 |
| ▸ | CETP | P11597 | 4/20 | 0.37 |
| ▸ | BAD | Q92934 | 2/20 | 0.36 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.36 |
| ▸ | BCL2L2 | Q92843 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5128718 | 0.85 | BCL2L1 (0.61) | BCL2L1BCL2CETPBAD | |
| SCHEMBL5128722 | 0.85 | BCL2L1 (0.61) | BCL2L1BCL2CETPBAD | |
| Hydrochloric Acid SCHEMBL5129185 | 0.84 | BCL2L1 (0.60) | BCL2L1BCL2CETPBAD | |
| SCHEMBL3819737 | 0.84 | BCL2L1 (0.60) | BCL2L1BCL2CETP | |
| Hydrochloric Acid SCHEMBL5131603 | 0.84 | BCL2L1 (0.59) | BCL2L1BCL2CETP | |
| SCHEMBL30857660 | 0.83 | BCL2L1 (0.58) | BCL2L1BCL2CETPBADBCL2L11 | |
| SCHEMBL30857750 | 0.83 | BCL2L1 (0.58) | BCL2L1BCL2CETPBADBCL2L11 | |
| SCHEMBL30857596 | 0.81 | BCL2L1 (0.44) | BCL2L1BCL2BADBCL2L11CYP2C9 | |
| SCHEMBL30857743 | 0.78 | BCL2L1 (0.69) | BCL2L1BCL2BADBCL2L11CYP2C9 | |
| SCHEMBL30857524 | 0.78 | BCL2L1 (0.71) | BCL2L1BCL2CETPBADBCL2L11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024067818-A1 | CHIMERIC COMPOUND USED FOR TARGETED DEGRADATION OF BCL-2 PROTEIN, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |