Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442419 | 0.86 | ALDH1A1 (0.58) | HDAC1MLYCDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11520102 | 0.84 | ALDH1A1 (0.56) | MLYCDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL1417508 | 0.84 | ALDH1A1 (0.56) | MLYCDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11513573 | 0.84 | ALDH1A1 (0.56) | MLYCDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL39138 | 0.84 | ALDH1A1 (0.56) | MLYCDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11473790 | 0.84 | ALDH1A1 (0.56) | MLYCDMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18626323 | 0.83 | MEN1 (0.44) | HDAC1MLYCDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2722703 | 0.80 | ALDH1A1 (0.60) | MLYCDMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28040046 | 0.79 | ALDH1A1 (0.50) | HDAC1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL28829229 | 0.78 | ALDH1A1 (0.48) | MLYCDMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635958-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2025-10-22 | — | — | EP | disclosed |
| WO-2024125642-A1 | PYRIMIDINE-CONTAINING POLYCYCLIC DERIVATIVE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-06-20 | — | — | WO | disclosed |
| WO-2024022444-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND MEDICINAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-02-01 | — | — | WO | disclosed |