Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30857793 | 0.83 | HDAC1 (0.48) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL5766910 | 0.78 | CA1 (0.49) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL28320279 | 0.77 | HDAC8 (0.43) | HTTHDAC1 | |
| SCHEMBL24404172 | 0.77 | HDAC8 (0.43) | HTTHDAC1 | |
| SCHEMBL11458527 | 0.77 | HDAC8 (0.43) | HTTHDAC1 | |
| SCHEMBL17696535 | 0.76 | CA12 (0.39) | HTTSMN1; SMN2HDAC1CA12CA1 | |
| SCHEMBL25039583 | 0.76 | GRIA4 (0.41) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL11848027 | 0.76 | TAS1R3 (0.35) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL11859053 | 0.76 | TAS1R3 (0.35) | MEN1KMT2ALMNAHTTSMN1; SMN2 | |
| SCHEMBL809800 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2ALMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593095-B2 | Methods for the treatment of bacterial infections | DUKE UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |