Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752634 | 0.74 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL15177769 | 0.71 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL5074095 | 0.71 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL13778886 | 0.67 | — | — | |
| SCHEMBL14550074 | 0.67 | HSD11B1 (0.31) | HSD11B1 | |
| SCHEMBL30798149 | 0.67 | HSD11B1 (0.33) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL4182332 | 0.65 | — | — | |
| SCHEMBL7893573 | 0.65 | NOS3 (0.31) | HSD11B1 | |
| SCHEMBL19173641 | 0.65 | — | — | |
| SCHEMBL30655841 | 0.64 | CHRM2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119365465-A | Condensed ring compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-01-24 | — | — | CN | disclosed |
| WO-2024022444-A1 | FUSED RING COMPOUND, PREPARATION METHOD THEREFOR AND MEDICINAL APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2024-02-01 | — | — | WO | disclosed |