Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859286 | 1.00 | MEN1 (0.43) | MEN1KMT2AJAK2MAPTALDH1A1 | |
| SCHEMBL27165401 | 1.00 | MEN1 (0.43) | MEN1KMT2AJAK2MAPTALDH1A1 | |
| SCHEMBL25838223 | 0.90 | MAPT (0.49) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL1816385 | 0.86 | KMT2A (0.49) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL5616615 | 0.83 | LMNA (0.44) | HTTMAPK1LMNA | |
| SCHEMBL13868731 | 0.82 | AKR1C3 (0.41) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL27165409 | 0.82 | AKR1C3 (0.52) | KMT2AMAPTALDH1A1HTTPRKDC | |
| SCHEMBL163753 | 0.82 | AKR1C3 (0.52) | KMT2AMAPTALDH1A1HTTPRKDC | |
| SCHEMBL24620659 | 0.81 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL25954142 | 0.81 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581021-A1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRAN COMPOUNDS, COMPOSITIONS, AND ARTICLES CONTAINING SAME | Transitions Optical, Ltd. (IE) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024046542-A1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRAN COMPOUNDS, COMPOSITIONS, AND ARTICLES CONTAINING SAME | TRANSITIONS OPTICAL, LTD. (IE) | 2024-03-07 | — | — | WO | disclosed |