Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27165409 | 1.00 | AKR1C3 (0.52) | AKR1C3KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL7134286 | 0.89 | MAPT (0.51) | AKR1C3KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL25954140 | 0.89 | KMT2A (0.41) | AKR1C3KMT2AMAPTRAB9AKDM4E | |
| SCHEMBL25954142 | 0.89 | MAPT (0.47) | AKR1C3KMT2AMAPTRAB9AKDM4E | |
| SCHEMBL24620659 | 0.89 | MAPT (0.47) | AKR1C3KMT2AMAPTRAB9AKDM4E | |
| SCHEMBL16313177 | 0.88 | MAPT (0.50) | KMT2AMAPTL3MBTL1RAB9AKDM4E | |
| SCHEMBL2018095 | 0.88 | MAPT (0.50) | KMT2AMAPTL3MBTL1RAB9AKDM4E | |
| SCHEMBL1962366 | 0.86 | KMT2A (0.48) | KMT2AMAPTL3MBTL1RAB9AKDM4E | |
| SCHEMBL26629621 | 0.86 | AKR1C3 (0.52) | AKR1C3KMT2AMAPTL3MBTL1RAB9A | |
| SCHEMBL1333002 | 0.86 | PRKDC (0.43) | AKR1C3KMT2AMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070881-A1 | Photochromic Indeno-Fused Naphthopyran Compounds, Compositions, and Articles Containing Same | TRANSITIONS OPTICAL LTD (IE) | 2026-03-12 | — | — | US | disclosed |
| EP-4581021-A1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRAN COMPOUNDS, COMPOSITIONS, AND ARTICLES CONTAINING SAME | Transitions Optical, Ltd. (IE) | 2025-07-09 | — | — | EP | disclosed |
| CN-119816488-A | Photochromic indeno-fused naphthopyran compounds, compositions and articles containing the same | 全视线光学有限公司 | 2025-04-11 | — | — | CN | disclosed |
| WO-2024046542-A1 | PHOTOCHROMIC INDENO-FUSED NAPHTHOPYRAN COMPOUNDS, COMPOSITIONS, AND ARTICLES CONTAINING SAME | TRANSITIONS OPTICAL, LTD. (IE) | 2024-03-07 | — | — | WO | disclosed |
| EP-4289831-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE AND EYEGLASSES | Hoya Lens Thailand Ltd. (TH) | 2023-12-13 | — | — | EP | disclosed |
| EP-3898636-B9 | INDOLONAPHTHOPYRANS | TRANSITIONS OPTICAL LTD (IE) | 2023-11-08 | — | — | EP | disclosed |
| US-20230340318-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | HOYA LENS THAILAND LTD. (TH) | 2023-10-26 | — | — | US | disclosed |
| US-20230340318-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | HOYA LENS THAILAND LTD. (TH) | 2023-10-26 | — | — | US | disclosed |
| EP-3898636-B1 | INDOLONAPHTHOPYRANS | TRANSITIONS OPTICAL LTD (IE) | 2023-08-30 | — | — | EP | disclosed |
| WO-2023140186-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2023-07-27 | — | — | WO | disclosed |
| US-20070215844-A1 | Chromene Compound | TOKUYAMA CORPORATION (JP) | 2007-09-20 | — | — | US | disclosed |
| EP-1214311-B1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-1097156-B1 | PHTOCHROMIC BENZOPYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1214311-A1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2002-06-19 | — | — | EP | disclosed |
| US-6353102-B1 | FOR OPHTHALMIC LENSES OR CONTACT LENSES | PPG INDUSTRIES OHIO, INC. | 2002-03-05 | — | — | US | disclosed |
| US-6296785-B1 | OPHTHALMIC AND CONTACT LENSES; WINDOWS, SAFETY GLASS FOR CARS | PPG INDUSTRIES OHIO, INC. | 2001-10-02 | — | — | US | disclosed |
| EP-1097156-A2 | PHTOCHROMIC BENZOPYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-05-09 | — | — | EP | disclosed |
| WO-2001019813-A1 | NOVEL INDENO-FUSED PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2001-03-22 | — | — | WO | disclosed |
| US-6022495-A | FOR OPTICAL APPLICATIONS | TRANSITIONS OPTICAL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| WO-2000002884-A2 | PHOTOCHROMIC BENZOPYRANO-FUSED NAPHTHOPYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260070881-A1 | Photochromic Indeno-Fused Naphthopyran Compounds, Compositions, and Articles Containing Same | CCND3, MRPS24, AP3S1 | AKR1C3 2339/4885KMT2A 3662/4885MAPT 2099/4885 |
| US-20070215844-A1 | Chromene Compound | CRY2, TYR, CRY1 | AKR1C3 1811/4885KMT2A 411/4885MAPT 520/4885 |
| US-20230340318-A1 | PHOTOCHROMIC COMPOUND, PHOTOCHROMIC COMPOSITION, PHOTOCHROMIC ARTICLE, AND EYEGLASSES | NR2E3, CRY1, RPS10 | AKR1C3 1484/4885KMT2A 2867/4885MAPT 3015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.