Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24783647 | 1.00 | TOP1 (0.43) | TOP1ALOX5TRAP1MGAMGAA | |
| SCHEMBL29180322 | 1.00 | TOP1 (0.43) | TOP1ALOX5TRAP1MGAMGAA | |
| SCHEMBL29234371 | 0.75 | PPARG (0.47) | ALOX5POLBTSHRADRA2AADRA1A | |
| SCHEMBL29234372 | 0.75 | PPARG (0.47) | ALOX5POLBTSHRADRA2AADRA1A | |
| SCHEMBL23635908 | 0.73 | HTR2A (0.40) | TRAP1MGAMGAASIMGAM2 | |
| SCHEMBL24783634 | 0.71 | TRAP1 (0.56) | ALOX5TRAP1TNKS2CYP3A4 | |
| SCHEMBL24783645 | 0.71 | TRAP1 (0.56) | ALOX5TRAP1TNKS2CYP3A4 | |
| SCHEMBL30859419 | 0.71 | TRAP1 (0.56) | ALOX5TRAP1TNKS2CYP3A4 | |
| SCHEMBL14894825 | 0.71 | TRAP1 (0.56) | ALOX5TRAP1TNKS2CYP3A4 | |
| SCHEMBL9081255 | 0.71 | ADRA2A (0.44) | TSHRADRA2AADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769559-A | TRAP1 inhibitors and uses thereof | 斯玛特恩生物公司 | 2024-03-26 | — | — | CN | disclosed |