Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.42 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 3/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859429 | 0.84 | ZDHHC7 (0.48) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL6703841 | 0.80 | ZDHHC7 (0.46) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL29767830 | 0.79 | ZDHHC7 (0.44) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL29767822 | 0.78 | ALOX5 (0.46) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL30859413 | 0.76 | ZDHHC7 (0.50) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL14707703 | 0.75 | L3MBTL1 (0.46) | ZDHHC7GAANPSR1 | |
| SCHEMBL4704070 | 0.67 | ZDHHC7 (0.72) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL10993066 | 0.67 | ZDHHC7 (0.72) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL5708286 | 0.67 | ZDHHC7 (0.72) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 | |
| SCHEMBL2721129 | 0.67 | ZDHHC7 (0.72) | ZDHHC7LCKPPARDZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117769559-A | TRAP1 inhibitors and uses thereof | 斯玛特恩生物公司 | 2024-03-26 | — | — | CN | disclosed |