SCHEMBL30860191

SCHEMBL30860191

O=C1c2ccccc2C(=O)N1c1n[nH]c2ccccc12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
KDM4E B2RXH2 6/20 0.44
GAA P10253 4/20 0.44
PDPK1 O15530 2/20 0.44
CYP3A4 P08684 2/20 0.44
HPGD P15428 3/20 0.44
MAPK1 P28482 2/20 0.44
HSD17B10 Q99714 2/20 0.44
ALDH1A1 P00352 5/20 0.44
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
TP53 P04637 1/20 0.44
ALPL P05186 6/20 0.43
POLB P06746 2/20 0.42
TTK P33981 2/20 0.42
MAPK10 P53779 2/20 0.42
IDO1 P14902 1/20 0.42
PARP1 P09874 1/20 0.40
LMNA P02545 3/20 0.39
HIF1A Q16665 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215547 1.00 CYP1A2 (0.46) CYP1A2KDM4EGAAPDPK1CYP3A4
SCHEMBL627900 0.82 GAA (0.45) GAAHSD17B10ALDH1A1ALPLPOLB
SCHEMBL31052682 0.82 ALPL (0.46) KDM4EGAAHPGDALDH1A1ALPL
SCHEMBL628631 0.82 ESR1 (0.47) GAAPDPK1HSD17B10ALDH1A1ALPL
SCHEMBL10112092 0.82 GSK3A (0.38) CYP1A2HPGDMAPK1HSD17B10ALDH1A1
SCHEMBL2993163 0.81 CYP1A2 (0.47) CYP1A2KDM4EGAAPDPK1CYP3A4
SCHEMBL627442 0.78 ALPL (0.49) CYP1A2KDM4EGAACYP3A4HPGD
SCHEMBL2634991 0.78 MAP2K4 (0.45) CYP1A2KDM4EPDPK1MAPK1CDK1
SCHEMBL30643584 0.77 CYP1A2 (0.44) CYP1A2KDM4EGAAPDPK1CYP3A4
SCHEMBL15995723 0.76 TP53 (0.42) MAPK1ALDH1A1TP53ALPLPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4603488-A1 NOVEL INDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF Korea University Research and Business Foundation (KR) 2025-08-20 EP disclosed
CN-120035587-A Novel indazole derivative or pharmaceutically acceptable salt thereof and use thereof 高丽大学校产学协力团 2025-05-23 CN disclosed
CN-118026880-A Aryl amide compound, pharmaceutical composition containing same and application thereof 华东师范大学 2024-05-14 CN disclosed
WO-2024080780-A1 NOVEL INDAZOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, AND USE THEREOF 고려대학교 산학협력단 2024-04-18 WO disclosed