Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.53 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | INSR | P06213 | 4/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.41 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30860740 | 0.93 | EGFR (0.54) | EGFRMETPLK1BTKLRRK2 | |
| SCHEMBL30860746 | 0.91 | EGFR (0.54) | EGFRMETPLK1BTKPTK2 | |
| SCHEMBL30860346 | 0.91 | EGFR (0.64) | EGFRMETPLK1BTKLRRK2 | |
| SCHEMBL30860243 | 0.90 | EGFR (0.51) | EGFRMETPLK1BTKLRRK2 | |
| SCHEMBL30860236 | 0.90 | EGFR (0.55) | EGFRMETPLK1BTKLRRK2 | |
| SCHEMBL30860277 | 0.88 | EGFR (0.51) | EGFRMETBTKINSRALK | |
| SCHEMBL30860753 | 0.88 | EGFR (0.50) | EGFRMETPLK1BTKLRRK2 | |
| SCHEMBL30860759 | 0.86 | EGFR (0.56) | EGFRMETBTKPTK2 | |
| SCHEMBL30860273 | 0.86 | EGFR (0.53) | EGFRMETBTKPTK2 | |
| SCHEMBL30860281 | 0.85 | EGFR (0.51) | EGFRMETBTKINSRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |