Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 15/20 | 0.60 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.47 |
| ▸ | INSR | P06213 | 3/20 | 0.47 |
| ▸ | IGF1R | P08069 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26906555 | 0.94 | EGFR (0.61) | EGFRALKINSRIGF1R | |
| SCHEMBL30860310 | 0.94 | EGFR (0.54) | EGFRALKINSRIGF1R | |
| SCHEMBL30860343 | 0.94 | EGFR (0.61) | EGFRALKINSRIGF1R | |
| SCHEMBL26906873 | 0.93 | EGFR (0.61) | EGFRALKINSRIGF1R | |
| SCHEMBL26907010 | 0.91 | EGFR (0.58) | EGFRALKINSRIGF1R | |
| SCHEMBL26906581 | 0.89 | EGFR (0.55) | EGFR | |
| SCHEMBL26906752 | 0.89 | EGFR (0.53) | EGFRALK | |
| SCHEMBL29904625 | 0.89 | EGFR (0.53) | EGFRALK | |
| SCHEMBL30659887 | 0.88 | EGFR (0.51) | EGFR | |
| SCHEMBL26906679 | 0.88 | EGFR (0.51) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | claimed |
| WO-2024072075-A1 | PYRIMIDINE DERIVATIVE HAVING PROTEIN KINASE INHIBITORY ACTIVITY, AND THERAPEUTIC PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 테라펙스 | 2024-04-04 | — | — | WO | disclosed |