Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27227845 | 1.00 | CREBBP (0.47) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL1780298 | 0.83 | CREBBP (0.46) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL27227902 | 0.83 | CREBBP (0.46) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL27227910 | 0.79 | CREBBP (0.49) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL22411798 | 0.79 | CREBBP (0.43) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL27227826 | 0.79 | VCAM1 (0.47) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL14272018 | 0.79 | CREBBP (0.75) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL22411925 | 0.79 | CREBBP (0.46) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL10596779 | 0.78 | HPRT1 (0.46) | CREBBPCYP3A4LMNAHTTALDH1A1 | |
| SCHEMBL15910918 | 0.78 | ERN1 (0.56) | CREBBPCYP3A4LMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |