Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27227891 | 1.00 | DCTPP1 (0.37) | DCTPP1TDP1VCAM1NOS1ALDH1A1 | |
| SCHEMBL27227809 | 0.85 | PKM (0.43) | TDP1NOS1ALDH1A1GAALMNA | |
| SCHEMBL27227908 | 0.80 | DDB1 (0.34) | — | |
| SCHEMBL27227871 | 0.79 | TDP1 (0.44) | TDP1NOS1ALDH1A1GAALMNA | |
| SCHEMBL30860978 | 0.79 | TDP1 (0.44) | TDP1NOS1ALDH1A1GAALMNA | |
| SCHEMBL30860975 | 0.79 | TDP1 (0.41) | DCTPP1TDP1NOS1ALDH1A1GAA | |
| SCHEMBL14910632 | 0.79 | TDP1 (0.41) | DCTPP1TDP1NOS1ALDH1A1GAA | |
| SCHEMBL27228485 | 0.76 | TDP1 (0.41) | TDP1NOS1ALDH1A1GAALMNA | |
| SCHEMBL27227986 | 0.74 | TDP1 (0.41) | TDP1NOS1ALDH1A1GAALMNA | |
| SCHEMBL27227877 | 0.73 | TDP1 (0.40) | TDP1NOS1ALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073073-A2 | KINASE MODULATORS AND METHODS OF USE THEREOF | NEURON23, INC. (US) | 2024-04-04 | — | — | WO | disclosed |