SCHEMBL3086175

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3090725	0.82	HRH3 (0.63)	HRH3CYP2D6CHRNA7TMEM97SIGMAR1
	SCHEMBL3094803	0.80	HRH3 (1.00)	HRH3CYP2D6HRH1GRIN1GRIN2B
	SCHEMBL3082636	0.78	HRH3 (1.00)	HRH3CYP2D6HRH1GRIN1GRIN2B
	SCHEMBL3089241	0.77	HRH3 (1.00)	HRH3CYP2D6TMEM97SIGMAR1HRH1
	SCHEMBL3099990	0.75	HTR2C (0.52)	CHRNA7HTR1AHTR2AHTR2CHTR2B
	SCHEMBL20755877	0.72	FFAR1 (0.57)	HTR1A
	SCHEMBL3087151	0.71	ESR2 (0.49)	CHRNA7
	SCHEMBL3089329	0.68	HRH3 (0.61)	HRH3CYP2D6CHRNA7GRIN2B
	SCHEMBL14429561	0.68	HRH3 (0.59)	HRH3CYP2D6TMEM97SIGMAR1HRH1
	SCHEMBL3101089	0.68	HRH3 (0.78)	HRH3CYP2D6HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.