Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 8/20 | 0.44 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527816 | 0.86 | ACE (0.56) | MAPTALDH1A1PTGS1MMEACE | |
| SCHEMBL31074242 | 0.86 | TGFBR1 (0.48) | MAPTALDH1A1PTGS1TGFBR1MME | |
| SCHEMBL29692973 | 0.85 | ALDH1A1 (0.50) | MAPTALDH1A1PTGS1MME | |
| SCHEMBL29378196 | 0.83 | ECE1 (0.51) | MAPTALDH1A1PTGS1ACECA2 | |
| SCHEMBL29540010 | 0.82 | ALDH1A1 (0.43) | MAPTALDH1A1PTGS1 | |
| SCHEMBL29379421 | 0.81 | ALDH1A1 (0.46) | MAPTALDH1A1PTGS1ACECA2 | |
| SCHEMBL29683631 | 0.80 | FOLH1 (0.50) | MAPTALDH1A1PTGS1 | |
| SCHEMBL30861862 | 0.80 | FNTA (0.48) | MAPTALDH1A1PTGS1 | |
| SCHEMBL29540181 | 0.79 | ALDH1A1 (0.43) | MAPTALDH1A1PTGS1ACE | |
| SCHEMBL31674469 | 0.77 | ALDH1A1 (0.57) | MAPTALDH1A1PTGS1MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118256591-A | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-06-28 | — | — | CN | disclosed |
| CN-110869544-B | Cyclic peptide compound having high membrane permeability and library comprising same | 中外制药株式会社 | 2024-03-08 | — | — | CN | disclosed |