SCHEMBL30863422

SCHEMBL30863422

COc1ccc(NC(=O)c2ccc(N3CCCN(C)CC3)c(F)c2)c2ccncc12

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ WDR5 P61964 4/20 0.49
▸ MEN1 O00255 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ FGFR1 P11362 2/20 0.48
▸ FGFR2 P21802 2/20 0.48
▸ F10 P00742 8/20 0.46
▸ ABCB1 P08183 1/20 0.45
▸ MAPT P10636 1/20 0.44
▸ KCNH2 Q12809 1/20 0.43
▸ SCN5A Q14524 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30863442 0.81 NPC1 (0.54) F10
SCHEMBL30863450 0.79 TRPV1 (0.57) WDR5FGFR1FGFR2MAPT
SCHEMBL27195688 0.79 TRPV1 (0.57) WDR5FGFR1FGFR2MAPT
SCHEMBL27195704 0.77 HTR1D (0.42) WDR5MEN1KMT2AABCB1MAPT
SCHEMBL30863420 0.77 HTR1D (0.42) WDR5MEN1KMT2AABCB1MAPT
Hydrochloric Acid SCHEMBL30863555 0.76 F10 (0.56) F10
SCHEMBL30863427 0.75 HDAC3 (0.52) FGFR1
SCHEMBL30863502 0.74 HDAC3 (0.59) WDR5F10
SCHEMBL9979804 0.73 F10 (0.76) F10
SCHEMBL30863419 0.73 WDR5 (0.44) WDR5MEN1KMT2AABCB1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP claimed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO claimed
EP-4581017-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS Biodol Therapeutics (FR) 2025-07-09 — — EP disclosed
WO-2024079072-A1 NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS BIODOL THERAPEUTICS (FR) 2024-04-18 — — WO disclosed
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