Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.58 |
| ▸ | EP300 | Q09472 | 2/20 | 0.56 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.56 |
| ▸ | AXL | P30530 | 1/20 | 0.50 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5661372 | 1.00 | IDO1 (0.58) | IDO1EP300KAT8AXLKAT2B | |
| SCHEMBL12426316 | 0.86 | MAOA (0.52) | IDO1EP300KAT8MAOACYP1A2 | |
| SCHEMBL5894746 | 0.80 | AXL (0.72) | EP300KAT8AXLKAT2BCYP3A4 | |
| SCHEMBL11086461 | 0.79 | MAOA (0.46) | IDO1EP300KAT8AXLKAT2B | |
| SCHEMBL2382250 | 0.78 | NTRK1 (0.57) | MAOACYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2381282 | 0.78 | AXL (0.55) | AXLMAOACYP3A4CYP1A2CYP2C19 | |
| SCHEMBL31483347 | 0.78 | AXL (0.55) | AXLMAOACYP3A4CYP1A2CYP2C19 | |
| SCHEMBL19660423 | 0.76 | MAOA (0.46) | IDO1EP300KAT8MAOACYP1A2 | |
| SCHEMBL14604837 | 0.75 | MAOA (0.42) | MAOACYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL14571327 | 0.75 | MAOA (0.42) | MAOACYP3A4CYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4581017-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | Biodol Therapeutics (FR) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024079072-A1 | NEW N-HETEROARYLBENZAMIDES DERIVATIVES AS FLT3 INHIBITORS | BIODOL THERAPEUTICS (FR) | 2024-04-18 | — | — | WO | disclosed |