Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 11/20 | 0.89 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.89 |
| ▸ | PGR | P06401 | 5/20 | 0.89 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.89 |
| ▸ | LMNA | P02545 | 2/20 | 0.89 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.89 |
| ▸ | AR | P10275 | 2/20 | 0.89 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.89 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.89 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.89 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.89 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.89 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.89 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.89 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253324 | 1.00 | NR3C1 (0.89) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL4568 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL2594997 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL8826257 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL12996648 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL25382496 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL4896227 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL7436523 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL600107 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA | |
| Mometasone Furoate SCHEMBL8430908 | 0.94 | CYP3A4 (1.00) | NR3C1CYP3A4PGRABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117849243-A | Impurity Z in mometasone furoate cream 3r And impurity Z 3q Method for separation and measurement of (2) | 重庆华邦制药有限公司 | 2024-04-09 | — | — | CN | disclosed |