Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31636996 | 0.88 | USP2 (0.39) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL368761 | 0.85 | USP2 (0.45) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL21636211 | 0.84 | USP2 (0.44) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL16465129 | 0.82 | FFAR4 (0.50) | USP2SMN1; SMN2RECQLDDB1CRBN | |
| SCHEMBL16465822 | 0.82 | GPR119 (0.47) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL17125240 | 0.82 | GPR119 (0.43) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL16465364 | 0.82 | NR1H2 (0.47) | USP2SMN1; SMN2RECQLHPGDGPR119 | |
| SCHEMBL18480992 | 0.81 | USP2 (0.41) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL16466158 | 0.81 | RECQL (0.43) | USP2SMN1; SMN2RECQLHPGDEPHX1 | |
| SCHEMBL23933137 | 0.80 | USP2 (0.39) | USP2SMN1; SMN2RECQLHPGDEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4606803-A1 | KRAS G12D DEGRADATION AGENT, AND PREPARATION METHOD AND USE THEREFOR | Leadingtac Pharmaceutical (Shaoxing) Co., Ltd. (CN) | 2025-08-27 | — | — | EP | disclosed |
| CN-117917416-A | KRAS G12D degradation agent and preparation method and application thereof | 上海领泰生物医药科技有限公司 | 2024-04-23 | — | — | CN | disclosed |