Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30864206 | 1.00 | TGFBR1 (0.59) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL30864195 | 0.86 | TGFBR1 (0.60) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL14881525 | 0.83 | TGFBR1 (0.66) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL20199773 | 0.81 | MAPT (0.47) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL15639375 | 0.81 | TGFBR1 (0.68) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL17781106 | 0.80 | TGFBR1 (0.62) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL30864196 | 0.80 | KDM4E (0.52) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL30864204 | 0.80 | KDM4E (0.52) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL23728465 | 0.79 | TGFBR1 (0.49) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL30864198 | 0.79 | HPGD (0.67) | TGFBR1SMN1; SMN2HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777142-A | Preparation method of 7-hydrogen substituted pyrazolo [1,5-a ] pyrimidine compound | 安徽中医药大学 | 2024-03-29 | — | — | CN | disclosed |