Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | HPGD | P15428 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.52 |
| ▸ | PDE2A | O00408 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30864204 | 1.00 | KDM4E (0.52) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL30864203 | 0.90 | KDM4E (0.55) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL4709283 | 0.89 | ALDH1A1 (0.53) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL30864198 | 0.87 | HPGD (0.67) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL30864194 | 0.87 | MAPT (0.61) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL312787 | 0.87 | TGFBR1 (0.55) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL17781064 | 0.85 | TGFBR1 (0.57) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL30864200 | 0.84 | MAPT (0.56) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL23728465 | 0.81 | TGFBR1 (0.49) | KDM4EALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL30864205 | 0.80 | TGFBR1 (0.59) | KDM4EALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117777142-A | Preparation method of 7-hydrogen substituted pyrazolo [1,5-a ] pyrimidine compound | 安徽中医药大学 | 2024-03-29 | — | — | CN | disclosed |