Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | CASP1 | P29466 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571141 | 1.00 | ALDH1A1 (0.48) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL4149010 | 0.81 | CASP3 (0.48) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL4141158 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL4141162 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL13926402 | 0.78 | KDM4E (0.42) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL2502232 | 0.77 | KDM4E (0.59) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL16413091 | 0.76 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL16412757 | 0.76 | ALDH1A1 (0.45) | ALDH1A1HSD17B10SMN1; SMN2CA1CA2 | |
| SCHEMBL21032890 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4ECASP1CASP7HSD17B10 | |
| SCHEMBL29715895 | 0.74 | NAMPT (0.50) | ALDH1A1KDM4ECASP1CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |