Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.41 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.41 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10324481 | 0.99 | L3MBTL1 (0.44) | L3MBTL1HCAR3PDE7ATEAD1TEAD4 | |
| SCHEMBL30040921 | 0.99 | L3MBTL1 (0.44) | L3MBTL1HCAR3PDE7ATEAD1TEAD4 | |
| SCHEMBL23535794 | 0.89 | NPC1 (0.41) | L3MBTL1RXRARXRBRXRGGAA | |
| SCHEMBL30040126 | 0.89 | NPC1 (0.41) | L3MBTL1RXRARXRBRXRGGAA | |
| SCHEMBL23535814 | 0.89 | SLC22A12 (0.46) | L3MBTL1HCAR3PDE7ARXRARXRB | |
| SCHEMBL30041514 | 0.89 | SLC22A12 (0.46) | L3MBTL1HCAR3PDE7ARXRARXRB | |
| Lithium Ion SCHEMBL28962278 | 0.88 | CYP4F2 (0.38) | L3MBTL1HCAR3PDE7ATEAD1TEAD4 | |
| Lithium Ion SCHEMBL30159606 | 0.88 | CYP4F2 (0.38) | L3MBTL1HCAR3PDE7ATEAD1TEAD4 | |
| SCHEMBL30159592 | 0.87 | DGAT2 (0.40) | PDE7ARXRARXRBRXRGGAA | |
| SCHEMBL10324149 | 0.87 | DGAT2 (0.40) | PDE7ARXRARXRBRXRGGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117858877-A | C-linked inhibitors of ENL/AF9 YEATS | 桥梁药品有限公司 | 2024-04-09 | — | — | CN | disclosed |