SCHEMBL3086448

SCHEMBL3086448

CCCCCCCCC([O])CCCCCC

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.52
PPARD Q03181 1/20 0.52
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52
TSHR P16473 1/20 0.50
THRB P10828 1/20 0.50
GPR84 Q9NQS5 3/20 0.48
FDPS P14324 3/20 0.48
FFAR1 O14842 1/20 0.48
LMNA P02545 1/20 0.48
DNM1 Q05193 4/20 0.48
ZDHHC7 Q9NXF8 1/20 0.46
MAPT P10636 1/20 0.46
OPRM1 P35372 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6434099 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL9873822 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL10436118 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL9533300 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL7700878 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL10335702 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL20420634 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL10335495 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL8862993 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR
SCHEMBL21799217 1.00 LCK (0.52) LCKPPARDZDHHC20ZDHHC2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3935052-A1 STERICALLY HINDERED AMINE STABILIZER MIXTURES BASF SE (DE) 2022-01-12 EP disclosed
WO-2020182587-A1 STERICALLY HINDERED AMINE STABILIZER MIXTURES BASF SE (DE) 2020-09-17 WO disclosed
US-20100279963-A1 DICARBONYL DERIVATIVES AND METHODS OF USE ABRAXIS BIOSCIENCE, LLC (US) 2010-11-04 US disclosed
US-7799954-B2 Dicarbonyl derivatives and methods of use ABRAXIS BIOSCIENCE, LLC (US) 2010-09-21 US disclosed
US-7674816-B2 Substituted melatonin derivatives, process for their preparation, and methods of use ABRAXIS BIOSCIENCE, LLC (US) 2010-03-09 US disclosed
EP-2125694-A2 DICARBONYL DERIVATIVES AND METHODS OF USE Abraxis BioScience, Inc. (US) 2009-12-02 EP disclosed
EP-1701718-A4 SUBSTITUTED MELATONIN DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND METHODS OF USE ABRAXIS BIOSCIENCE LLC (US) 2009-06-24 EP disclosed
EP-1976505-A1 COMBRETASTATIN DERIVATIVES AND RELATED THERAPEUTIC METHODS Abraxis BioScience, Inc. (US) 2008-10-08 EP disclosed
US-20080146586-A1 DICARBONYL DERIVATIVES AND METHODS OF USE ABRAXIS BIOSCIENCE (US) 2008-06-19 US disclosed
WO-2008064060-A2 DICARBONYL DERIVATIVES AND METHODS OF USE ABRAXIS BIOSCIENCE, INC. (US) 2008-05-29 WO disclosed
EP-1553443-A1 SILVER HALIDE PHOTOSENSITIVE MATERIAL AND METHOD OF FORMING IMAGE Konica Minolta Photo Imaging, Inc. (JP) 2005-07-13 EP disclosed
US-6171774-B1 YELLOW IMAGE-FORMING EMULSION LAYER CONTAINS A YELLOW DYE-FORMING COUPLER AND AN ORGANIC SOLVENT-SOLUBLE POLYMER KONICA CORPORATION (JP) 2001-01-09 US disclosed
US-5928850-A WITH OXAZOLIDIONE-TYPE YELLOW COUPLER KONICA CORPORATION (JP) 1999-07-27 US disclosed
US-5650430-A Radicicol derivatives, their preparation and their anti-tumor activity SANKYO COMPANY, LIMITED (JP) 1997-07-22 US disclosed
EP-0460950-B1 Radicicol derivatives, their preparation and their anti-tumour activity SANKYO CO (JP) 1997-03-05 EP disclosed
US-5597846-A ESTERS OF RADICICOL SANKYO COMPANY, LIMITED (JP) 1997-01-28 US disclosed
WO-1991018905-A1 RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY SANKYO COMPANY LIMITED (JP) 1991-12-12 WO disclosed
EP-0460950-A1 Radicicol derivatives, their preparation and their anti-tumour activity Sankyo Company Limited (JP) 1991-12-11 EP disclosed
EP-0357702-A1 FLUORINATED OLIGOPHENYL DERIVATIVES. MERCK PATENT GMBH (DE) 1990-03-14 EP disclosed
WO-1989006678-A1 FLUORINATED OLIGOPHENYL DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-07-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080146586-A1 DICARBONYL DERIVATIVES AND METHODS OF USE AADAC, DCK, MLYCD LCK 4583/4885PPARD 3374/4885ZDHHC20 2845/4885
US-20100279963-A1 DICARBONYL DERIVATIVES AND METHODS OF USE AADAC, DCK, MLYCD LCK 4583/4885PPARD 3374/4885ZDHHC20 2845/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.