Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.53 |
| ▸ | LMNA | P02545 | 8/20 | 0.53 |
| ▸ | HTT | P42858 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27083327 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL27083360 | 0.80 | SMN1; SMN2 (0.73) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL27083318 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL30865005 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL27083363 | 0.79 | SMN1; SMN2 (0.82) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL27083375 | 0.78 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL27083382 | 0.77 | SMN1; SMN2 (0.64) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL27083316 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL27083334 | 0.76 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHTTRAB9ANPC1 | |
| SCHEMBL30864995 | 0.76 | PDE3B (0.63) | SMN1; SMN2LMNAHTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240043384-A1 | INHIBITORS OF PU.1 FOR THE TREATMENT OF DISEASE | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2024-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240043384-A1 | INHIBITORS OF PU.1 FOR THE TREATMENT OF DISEASE | CREBBP, JUN, SP1 | SMN1; SMN2 763/4885LMNA 2795/4885HTT 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.