Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30865114 | 0.89 | MGLL (0.41) | MGLLMEN1TSHRKMT2ANPSR1 | |
| SCHEMBL30865266 | 0.82 | MGLL (0.53) | MGLL | |
| SCHEMBL30865326 | 0.81 | MGLL (0.52) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30865159 | 0.81 | MGLL (0.65) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30865183 | 0.81 | MGLL (0.57) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30865279 | 0.81 | MGLL (0.56) | MGLLCYP3A4CYP2D6IDO1 | |
| SCHEMBL30865390 | 0.81 | MGLL (0.53) | MGLL | |
| SCHEMBL30865414 | 0.81 | MGLL (0.60) | MGLL | |
| SCHEMBL30865457 | 0.81 | MGLL (0.59) | MGLL | |
| SCHEMBL30013286 | 0.80 | MGLL (0.57) | MGLLCYP3A4CYP2D6IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | claimed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | claimed |
| EP-4608823-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. Hoffmann-La Roche AG (CH) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088922-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-02 | — | — | WO | disclosed |