SCHEMBL30865390

SCHEMBL30865390

O=C(N1CC2(CC(n3cnc(C4CC4)n3)C2)C1)N1CC2(CN(Cc3nccn3C(F)(F)F)C2)C1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ MGLL Q99685 6/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30865271 0.88 MGLL (0.57) MGLL
SCHEMBL30865319 0.88 MGLL (0.41) MGLL
SCHEMBL30865326 0.86 MGLL (0.52) MGLL
SCHEMBL30865380 0.82 MGLL (0.53) MGLL
SCHEMBL30865434 0.82 MGLL (0.53) MGLL
SCHEMBL30865244 0.81 MGLL (0.54) MGLL
SCHEMBL30865375 0.81 MGLL (0.60) MGLL
SCHEMBL30865169 0.81 MGLL (0.40) MGLL
SCHEMBL30865414 0.80 MGLL (0.60) MGLL
SCHEMBL25325543 0.80 MGLL (0.36) MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608823-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) F. Hoffmann-La Roche AG (CH) 2025-09-03 — — EP claimed
WO-2024088922-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) F. HOFFMANN-LA ROCHE AG (CH) 2024-05-02 — — WO claimed
EP-4608823-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) F. Hoffmann-La Roche AG (CH) 2025-09-03 — — EP disclosed
WO-2024088922-A1 HETEROCYCLIC COMPOUNDS AS INHIBITORS OF MONOACYLGLYCEROL LIPASE (MAGL) F. HOFFMANN-LA ROCHE AG (CH) 2024-05-02 — — WO disclosed
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