Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731405 | 0.75 | — | — | |
| SCHEMBL218480 | 0.70 | — | — | |
| SCHEMBL479263 | 0.69 | HRH4 (0.39) | HRH4HRH3ADRB2HTR1BNR2E1 | |
| SCHEMBL2600364 | 0.69 | HRH4 (0.43) | HRH4HRH3ADRB2HTR1BNR2E1 | |
| SCHEMBL8363351 | 0.68 | — | — | |
| SCHEMBL754871 | 0.67 | HRH4 (0.45) | HRH4HRH3ADRB2HTR1BNR2E1 | |
| SCHEMBL19350614 | 0.67 | HRH4 (0.45) | HRH4HRH3ADRB2HTR1BNR2E1 | |
| SCHEMBL4789143 | 0.67 | HRH4 (0.45) | HRH4HRH3ADRB2HTR1BNR2E1 | |
| SCHEMBL841330 | 0.67 | HRH4 (0.45) | HRH4HRH3ADRB2HTR1BNR2E1 | |
| SCHEMBL2479475 | 0.67 | HRH4 (0.45) | HRH4HRH3ADRB2HTR1BNR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100233104-A1 | Amino-Acid Functional Siloxanes, Methods Of Preparation and Applications | DOW CORNING LIMITED (GB) | 2010-09-16 | — | — | US | disclosed |
| EP-2024423-B1 | AMINO-ACID FUNCTIONAL SILOXANES, METHODS OF PREPARATION AND APPLICATIONS | DOW CORNING (US) | 2009-12-09 | — | — | EP | disclosed |
| EP-2024423-A2 | AMINO-ACID FUNCTIONAL SILOXANES, METHODS OF PREPARATION AND APPLICATIONS | Dow Corning Corporation (US) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007141565-A2 | AMINO-ACID FUNCTIONAL SILOXANES, METHODS OF PREPARATION AND APPLICATIONS | DOW CORNING CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100233104-A1 | Amino-Acid Functional Siloxanes, Methods Of Preparation and Applications | DAO, AADAT, BCAT2 | HRH4 616/4885HRH3 474/4885ADRB2 3550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.