Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29540564 | 0.86 | FGFR1 (0.33) | AXLNUDT1FGFR1KDR | |
| SCHEMBL28810839 | 0.74 | KDR (0.52) | AXLNUDT1FGFR1KDR | |
| SCHEMBL32663536 | 0.73 | DYRK1A (0.34) | — | |
| SCHEMBL26695951 | 0.73 | DYRK1A (0.34) | — | |
| SCHEMBL29944813 | 0.70 | FGFR1 (0.35) | AXLNUDT1FGFR1KDR | |
| SCHEMBL27963553 | 0.69 | MAPK1 (0.45) | — | |
| SCHEMBL30968330 | 0.69 | — | — | |
| SCHEMBL9101975 | 0.67 | PRKCI (0.41) | AXLNUDT1FGFR1KDR | |
| SCHEMBL30745947 | 0.66 | AXL (0.39) | AXLNUDT1FGFR1KDR | |
| SCHEMBL20657263 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024061118-A1 | MACROCYCLIC NITROGEN-CONTAINING CROWN ETHER COMPOUND AND USE THEREOF AS PROTEIN KINASE INHIBITOR | 科辉智药生物科技（无锡）有限公司 | 2024-03-28 | — | — | WO | disclosed |