Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.64 |
| ▸ | MMP12 | P39900 | 1/20 | 0.64 |
| ▸ | NR1I2 | O75469 | 10/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088796 | 0.91 | PRKCA (0.64) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| SCHEMBL3093143 | 0.88 | PRKCA (0.82) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| SCHEMBL3089838 | 0.87 | PRKCA (0.63) | PRKCAMMP12NR1I2CYP3A4KCNH2 | |
| SCHEMBL3092955 | 0.87 | PRKCA (0.76) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| Trifluoroacetic Acid SCHEMBL1244063 | 0.87 | PRKCA (0.73) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| SCHEMBL3098597 | 0.84 | PRKCA (0.55) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| SCHEMBL3092202 | 0.84 | PRKCA (0.67) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| SCHEMBL3567697 | 0.81 | PRKCA (0.60) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| SCHEMBL3089205 | 0.80 | PRKCA (0.66) | PRKCAMMP12NR1I2CYP3A4CYP2C19 | |
| SCHEMBL4206539 | 0.79 | PRKCA (0.66) | PRKCAMMP12NR1I2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | claimed |