Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.66 |
| ▸ | MMP12 | P39900 | 1/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206539 | 0.90 | PRKCA (0.66) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL3092955 | 0.89 | PRKCA (0.76) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL3088711 | 0.88 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL2957655 | 0.88 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL3087122 | 0.87 | PRKCA (0.61) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL4211294 | 0.86 | PRKCA (0.59) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL3086916 | 0.85 | PRKCA (0.60) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| Trifluoroacetic Acid SCHEMBL1244063 | 0.85 | PRKCA (0.73) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL3096348 | 0.85 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9ACYP3A4 | |
| SCHEMBL2957529 | 0.85 | PRKCA (0.70) | PRKCAMMP12NR1I2SCN9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7795247-B2 | Tetracyclic indole derivatives as antiviral agents | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-14 | — | — | US | claimed |