SCHEMBL3086593

SCHEMBL3086593

O=C(O)Oc1cc(Br)c(C(F)F)[nH]c1=O

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30
GRIA1 P42261 1/20 0.30
GRIA2 P42262 1/20 0.30
GRIA4 P48058 1/20 0.30
GRIK5 Q16478 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3071416 0.69 HSD17B2 (0.34)
SCHEMBL16372089 0.65 GAA (0.55)
SCHEMBL4862450 0.64 LCK (0.39) LCKFYN
SCHEMBL16372116 0.62 HSD17B1 (0.43)
SCHEMBL16371315 0.61 DAO (0.30)
SCHEMBL1061623 0.61 GAA (0.48)
SCHEMBL9688765 0.61 DAO (0.54)
SCHEMBL8169849 0.60 NPC1 (0.36) LCKFYN
SCHEMBL17026756 0.60 LCK (0.36) LCKFYN
SCHEMBL323191 0.59 TNFSF11 (0.39) LCKFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144879-A2 PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF Bayer CropScience AG (DE) 2010-01-20 EP disclosed
WO-2008131860-A2 PYRIDONECARBOXAMIDES CROP PROTECTION AGENTS CONTAINING THE SAME METHOD FOR PRODUCTION AND USE THEREOF BAYER CROPSCIENCE AG (DE) 2008-11-06 WO disclosed