Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PER2 | O15055 | 1/20 | 0.40 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.40 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29240177 | 1.00 | LMNA (0.46) | LMNATP53ATMCNR2MEN1 | |
| SCHEMBL29240190 | 0.89 | P2RX4 (0.52) | LMNATP53MEN1KMT2AP2RX4 | |
| SCHEMBL30866065 | 0.89 | P2RX4 (0.52) | LMNATP53MEN1KMT2AP2RX4 | |
| SCHEMBL29240178 | 0.89 | KDM4E (0.50) | LMNATP53MEN1KMT2AP2RX4 | |
| SCHEMBL30866020 | 0.89 | KDM4E (0.50) | LMNATP53MEN1KMT2AP2RX4 | |
| SCHEMBL30866012 | 0.88 | P2RX4 (0.41) | LMNATP53MEN1KMT2AP2RX4 | |
| SCHEMBL30866045 | 0.88 | KDM4E (0.44) | LMNATP53P2RX4POLBALDH1A1 | |
| SCHEMBL29240191 | 0.88 | KDM4E (0.44) | LMNATP53P2RX4POLBALDH1A1 | |
| SCHEMBL29240225 | 0.88 | P2RX4 (0.41) | LMNATP53MEN1KMT2AP2RX4 | |
| SCHEMBL29240206 | 0.86 | VKORC1 (0.44) | LMNACNR2P2RX4POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117917400-A | 2-Methyl-4-quinolinone compound, and pharmaceutical composition and application thereof | 暨南大学 | 2024-04-23 | — | — | CN | disclosed |